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What are the complications of chronic kidney disease?

If your kidneys aren’t working properly, the rest of your body isn’t either. Some of the complications of chronic kidney disease include:

Low red blood cell count (anemia).

Weak and brittle bones.

Gout.

Metabolic acidosis. This is a chemical imbalance (acid-base) in your blood caused by decrease in kidney function.

High blood pressure.

Heart disease, including increased risk of stroke and heart attack.

High potassium (hyperkalemia), which affects your heart’s ability to function correctly.

High phosphorus (hyperphosphatemia).

Fluid buildup, leading to swelling in feet, ankles and hands; fluid in your lungs.

Erectile dysfunction, fertility problems.

Decreased immune response, increasing your risk of infection.

What can I expect if I have kidney disease?

If you have kidney disease you can still live a productive home and work life and enjoy time with your family and friends. To have the best outcome possible, it’s important for you to become an active member of your treatment team.

Early detection and appropriate treatment are important in slowing the disease process, with the goal of preventing or delaying kidney failure. You will need to keep your medical appointments, take your medications as prescribed, stick to a healthy diet and monitor your blood pressure and blood sugar.

Can kidney disease be prevented?

Seeing your healthcare provider on a regular basis throughout your life is a good start for preventing kidney disease. About one in every three people in the United States is at risk for kidney disease. Identify and manage any risk factors for developing kidney disease.

Manage your high blood pressure. Normal blood pressure is 120/80.

Manage your blood sugar if you have diabetes.

Eat a healthy diet. Follow a low-fat, low-salt diet.

Don’t smoke.

Be active for 30 minutes at least five days a week.

Maintain a healthy weight.

Take nonprescription pain relievers only as directed. Taking more than directed can damage your kidneys.

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First your healthcare provider will take your medical history, conduct a physical exam, ask about any medication you are currently taking, ask about any symptoms you have noticed, and inquire if any of your family members have kidney disease.

Your healthcare provider will order blood tests, a urine test and will also check your blood pressure.

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The blood tests will check: Your glomerulofiltration rate (GFR). This describes how efficiently your kidneys are filtering blood – how many milliliters per minute your kidneys are filtering. Your GFR is used to determine the stage of your kidney disease.

Your serum creatinine level, which tells how well your kidneys are removing this waste product. Creatinine is a waste product from muscle metabolism and is normally excreted in your urine. A high creatinine level in your blood means that your kidneys are not functioning well enough to get rid it in your urine.

A urine protein test will look for the presence of protein (albumin) and blood in your urine. Well-functioning kidneys should not have blood or proteins in your urine. If you do, this means your kidneys are damaged.

Other tests may include imaging tests to look for problems with the size and structure of your kidneys such as ultrasound, magnetic resonance imaging (MRI) and/or computerized tomography (CT) scans. Your healthcare provider may also order a kidney biopsy to check for a specific type of kidney disease or to determine the amount of kidney damage. In this procedure, performed using local anesthesia, a piece of your kidney tissue is removed and examined.

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How is chronic kidney disease treated?

There is no cure for chronic kidney disease (CKD), but steps may be taken in early CKD to preserve a higher level of kidney function for a longer period of time. If you have reduced kidney function:

Make and keep your regular healthcare provider / nephrologist (kidney specialist) visits.

Manage your blood sugar if you have diabetes.

Avoid taking painkillers and other medications that may make your kidney disease worse.

Manage your blood pressure levels.

Consult a dietitian regarding useful changes in diet. Dietary changes may include limiting protein, eating foods that reduce blood cholesterol levels, and limiting sodium (salt) and potassium intake.

Don’t smoke.

Treat anemia (if present).

Exercise/be active on most days of the week.

Stay at a healthy weight.

What medications are prescribed for people with chronic kidney disease?

Depending on the cause of your kidney disease, you may be prescribed one or more medications. Medications your nephrologist may prescribe include:

An angiotensin-converting enzyme (ACE) inhibitor or an angiotensin receptor blocker (ARB) to lower your blood pressure.

A diuretic to help your body eliminate extra fluid.

Medications to lower cholesterol levels.

Erythropoetin, to build red blood cells if you are anemic.

Vitamin D and calcitrol to prevent bone loss.

Phosphate binder if your kidneys can’t eliminate phosphate.

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What is kidney dialysis?

Because there is no cure for CKD, if you are in late-stage disease, you and your healthcare team must consider additional options. Complete kidney failure, left untreated, will result in death. Options for end stages of CKD include dialysis and kidney transplantation.

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