Why Do Some Of Us Get COVID / XE But Others Don't?: Expectations vs. Reality

Why Do Some Of Us Get COVID / XE But Others Don't?: Expectations vs. Reality

The Next Big Thing in Why Do Some Of Us Get Covid But Others Don't?

In this article, I have tried to explain the reality behind COVID vs No COVID

According to WHO, the BA2 subvariation (Covid 19) is 10% more common than the new type. On the other hand, the health ministry observed significant inconsistencies in disease transmission and features, including severity. COVID-19 strain XE, according to the WHO, maybe be more spreadable than any other strain.

1. People who have never been infected with the coronavirus are known as "no COVID" or "never COVID."

Many of us have not been infected by the coronavirus while living in the same area and under the same conditions. So, despite being infected with the severe coronavirus, what makes these people "invincible" to it? These individuals, also known as "no COVID" or "never COVID," not only shield themselves from viral infections but also help to minimize viral transmission in various ways.

2. People who haven't been infected with COVID?

These are the persons who have been fortunate enough not to have been infected with the coronavirus, which has infected 440,807,756 people worldwide to date.

COVID, which is caused by the coronavirus, was initially discovered in China's Wuhan region in November 2019. The World Health Organization called it a global epidemic a few months later (WHO). Since then, the entire planet has been gripped by the COVID infection, which has arrived in waves with varying symptoms and severity.

The WHO has classified five mutated coronavirus strains as variants of concern so far.

To reduce the risk of COVID, governments around the world have implemented lockdowns at the local level. People have trained themselves to stay away from the virus during the last two years by staying indoors, working from home, and limiting travel.

However, despite living in the same environment as those who have been infected, there is a group of people among us who have not received the virus.

3. What is the cause of their invulnerability?

According to a study performed by Imperial College London, several people had larger amounts of T cells, a type of immune memory cell developed from other common cold coronaviruses, and these people have immunity to the current coronavirus that causes COVID.

Doctors discovered large amounts of pre-existing T cells, which are formed by the body when infected with other human coronaviruses like the common cold, in their studies.

A variety of coronaviruses exist, many of which are associated with common colds. Even though all coronaviruses behave differently, the study found that they share some traits. It's possible that because of this similarity, immune cells recognize them and fight them off as soon as the body is exposed to them, which is why the person does not contract COVID.

4. COVID-free people versus asymptomatic persons.

Everybody knows that asymptomatic people don't display any symptoms, but they're just as responsible for the virus's spread as infected people.

The term "no-COVID" refers to those who are free of the virus or the sickness. These people have a virus-fighting immune system that is far too strong. They are unlikely to spread the disease because they do not have the virus in their bodies.

5. Is it no screening or immunity?

This could lead to a debate. We're all aware of the distorted nature of COVID testing. Under-testing has been a source of concern for health professionals and scientists, and it is thought to be impeding study into the infection.

Under-testing is a major concern because it was previously the sole means to distinguish between symptomatic and asymptomatic people. Many asymptomatic people forego testing because they don't show symptoms of the disease; as a result, they may believe they have "high immunity," yet they contribute just as much to the spread of the infection as those who are sick.

6. What do the genes have to say about it?

Individual susceptibility to COVID is determined in part by genetic factors. The interaction between genetics and the immune system and COVID-19 infection has been discovered to be essential in studies.

The behavior of human leukocyte antigens, according to researchers, determines one's response to COVID."Human leukocyte antigen genes, often known as HLA genes, are crucial genes that control your immune response. They'll help you figure out how you'll react if you come into touch with SARS-CoV-2. "Those with the gene HLA-DRB1*1302 are substantially more likely to suffer symptomatic sickness," says Danny Altmann, an immunology expert at Imperial College London.

7. Is vaccination required for these individuals?

What if you've merely been fortunate up to this point? Given the emergence of new viral variations and infectious waves, the prospect of remaining virus-free in the future cannot be ruled out.

Vaccination has proven to be the most effective weapon against the virus thus far. It's possible that the Omicron type of coronavirus hasn't had a severe impact on humans because of vaccination.

Getting vaccinated is a must if you want to protect yourself against viruses. One should not only get vaccinated but also receive a prophylactic dosage or booster shot at the proper time.

8. What function do immunizations play?

Is it possible that these "no COVID" people were not infected during the first wave and that their bodies developed immunity to the virus as a result of early vaccination, rendering the virus impossible to infiltrate? There's a good chance it'll happen.

COVID vaccination is said to be effective by scientists and health specialists. Vaccination programs around the world were blamed for the Omicron wave's reduced intensity and minimal hospitalizations.

Experts have suggested that cross-reactive immunity and immunizations benefit these individuals as a probable reason why many people do not have COVID." Certainly, cross-reactive immunity from past infections with common cold coronavirus is likely to be a substantial effect," Lawrence Young, a professor of molecular oncology at Warwick University, told the media. "Especially because immunization may provide additional immunological benefits for these persons."

9. Conclusion

Finally, the discovered humble requests/suggestions are that everyone should follow the guidelines / advisory issues issued by global, national, regional, and local authorities regularly, rather than relying on their unscientific assumptions or thumb rules so that others are not harmed/affected by our silly activities.