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How to select the best Vitamin E?

Tocopherols vs Tocotrienols

By Ng JayvinPublished about a year ago 3 min read
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What is Vitamin E?

Vitamin E is a fat-soluble vitamin that plays an important role in maintaining overall health and well-being. It is a group of eight different compounds, including alpha-tocopherol, beta-tocopherol, gamma-tocopherol, delta-tocopherol, alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol, and delta-tocotrienol.

As an antioxidant, vitamin E helps to protect cells from damage caused by free radicals, which are unstable molecules that can damage cells and contribute to the development of various health problems, including heart disease, cancer, and cognitive decline. Vitamin E is also involved in immune function, cell signaling, and gene expression.

Vitamin E can be obtained from a variety of dietary sources, including nuts, seeds, vegetable oils, leafy green vegetables, and fortified cereals and other foods. It can also be taken in supplement form, although it is generally recommended to obtain nutrients from whole foods whenever possible.

While vitamin E deficiency is rare, it can occur in individuals with certain health conditions or those who have difficulty absorbing fat. Symptoms of vitamin E deficiency may include muscle weakness, vision problems, and impaired immune function.

Differences between Tocopherols vs Tocotrienols?

Tocotrienols and tocopherols are both types of vitamin E compounds, but they differ in their chemical structure and biological activity. Tocotrienols have an unsaturated side chain with three double bonds, while tocopherols have a saturated side chain with no double bonds.

In terms of biological activity, research suggests that tocotrienols may have more potent antioxidant and anti-inflammatory effects compared to tocopherols. Tocotrienols have also been shown to have potential health benefits for various conditions, including cardiovascular disease, cancer, and neurodegenerative diseases, that are not seen with tocopherols.

However, the current understanding of the health effects of tocotrienols is still limited, and more research is needed to fully understand their benefits and mechanisms of action. In general, a balanced intake of both tocotrienols and tocopherols may be beneficial for overall health.

When do we need Vitamin E?

As an antioxidant: Vitamin E is a potent antioxidant that helps to protect cells from damage caused by free radicals. Individuals who are exposed to high levels of oxidative stress, such as smokers or people who live in polluted areas, may benefit from increased vitamin E intake.

Inflammation: Vitamin E has been shown to have anti-inflammatory effects, which may be beneficial for individuals with chronic inflammatory conditions, such as rheumatoid arthritis.

Skin health: Vitamin E is important for maintaining healthy skin, and topical application of vitamin E has been shown to improve skin texture and reduce the appearance of fine lines and wrinkles.

Eye health: Vitamin E is also important for maintaining eye health, and studies suggest that it may help to reduce the risk of age-related macular degeneration, a leading cause of vision loss in older adults.

Cognitive function: Vitamin E may also play a role in maintaining cognitive function and reducing the risk of cognitive decline in older adults.

Where to get Tocotrienol Vitamin E?

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In a nutshell

Tocotrienols and tocopherols can both penetrate cell membranes due to their lipophilic (fat-loving) nature, which allows them to interact with and protect cell membranes from oxidative damage caused by free radicals. However, studies suggest that tocotrienols may have superior cellular penetration and distribution compared to tocopherols.

This is because tocotrienols have a smaller and more flexible structure compared to tocopherols, which allows them to more easily traverse cell membranes and reach deeper into tissues. In addition, tocotrienols have been shown to have higher binding affinity to proteins involved in cellular transport and metabolism, which may enhance their cellular uptake and distribution.

Studies have also suggested that tocotrienols may be more effective than tocopherols in protecting against oxidative damage in certain tissues, such as the brain and liver. For example, one study found that tocotrienols were more effective at reducing oxidative stress and inflammation in the brains of mice with induced traumatic brain injury compared to tocopherols.

Overall, while both tocotrienols and tocopherols can penetrate cell membranes and protect against oxidative damage, tocotrienols may have certain advantages in terms of cellular uptake and distribution, as well as their effectiveness in protecting against oxidative damage in certain tissues.

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