beauty
Beauty topics, products, tips, and advice presented by Filthy.
High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). Early phase clinical trials have confirmed safety and indicated efficacy of IVC in eradicating tumour cells of various cancer types. In recent years, the multi-targeting effects of vitamin C were unravelled, demonstrating a role as cancer-specific, pro-oxidative cytotoxic agent, anti-cancer epigenetic regulator and immune modulator, reversing epithelial-to-mesenchymal transition, inhibiting hypoxia and oncogenic kinase signalling and boosting immune response. Moreover, high-dose IVC is powerful as an adjuvant treatment for cancer, acting synergistically with many standard (chemo-) therapies, as well as a method for mitigating the toxic side-effects of chemotherapy. Despite the rationale and ample evidence, strong clinical data and phase III studies are lacking. Therefore, there is a need for more extensive awareness of the use of this highly promising, non-toxic cancer treatment in the clinical setting. In this review, we provide an elaborate overview of pre-clinical and clinical studies using high-dose IVC as anti-cancer agent, as well as a detailed evaluation of the main known molecular mechanisms involved. A special focus is put on global molecular profiling studies in this respect. In addition, an outlook on future implications of high-dose vitamin C in cancer treatment is presented and recommendations for further research are discussed.
By Viva Infusionsabout a year ago in Filthy
Positivity
Positivity: The Power of a Positive Mindset In today's fast-paced and often stressful world, it's easy to get caught up in negativity and pessimism. From the constant barrage of news stories highlighting the world's problems to the challenges we face in our personal lives, it's easy to feel overwhelmed and discouraged. But what if we shifted our focus to the positive? What if we made a conscious effort to cultivate a positive mindset?
By Openee Article about a year ago in Filthy
Bulimia compulsive disorder: causes and treatment
Berlin - Bulimia compulsive disorder is a psychological disorder that mostly affects women, and it means eating large amounts of food more than what the body needs, which often leads to significant weight gain, according to what the German Society for Psychiatry, Psychotherapy and Neurology said.
By News Correctabout a year ago in Filthy
Physical activity, even for a limited time, contributes to reducing the risk of death
The need to perform exercise, even for a short period Doctors and fitness experts stress the importance of exercising even for a short period of time, as a slight increase in movement in inactive people is sufficient to provide them with significant protection. Experts confirm that physical activity protects against the risk of death, and point out that brisk walking is a moderate to intense activity, and they suggest, for example, the idea of walking to the workplace.
By News Correctabout a year ago in Filthy
Donetsk surgeons save a patient with a bullet wound to the heart
The Minister of Health of the Donetsk Republic, Dmitry Gartsev, said in a statement to "Novosti" agency, "A 36-year-old man was hospitalized with shrapnel, and after taking a medical picture, the team noticed the presence of a foreign body (bullet) in (the surrounding membrane). with the heart).
By News Correctabout a year ago in Filthy
How I lost 117 pounds in just 60 days, by eating healthy food
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By Saawuan Emmanuel Tabout a year ago in Filthy